Adaptation of enterovirus 71 to adult interferon deficient mice.

Non-polio enteroviruses, including enterovirus 71 (EV71), have caused severe and fatal cases of hand, foot and mouth disease (HFMD) in the Asia-Pacific region. The development of a vaccine or antiviral against these pathogens has been hampered by the lack of a reliable small animal model. In this st...

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Bibliographic Details
Main Authors: Elizabeth A Caine, Charalambos D Partidos, Joseph D Santangelo, Jorge E Osorio
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3602422?pdf=render