Microalbuminuria In Nondiabetic Acute Ischaemic Stroke - An Indian Perspective

• Main Authors: Mathur PC, Punckar Prashant, Muralidharan Rajesh
• Format: Article
• Language: English
• Published: Wolters Kluwer Medknow Publications 2005-01-01
• Series: Annals of Indian Academy of Neurology
• Online Access: http://www.annalsofian.org/article.asp?issn=0972-2327;year=2005;volume=8;issue=4;spage=237;epage=242;aulast=Mathur;type=0

To investigate the incidence, relationship to risk factors and severity of stroke with microalbuminuria (MA) in nondiabetic acute ischaemic stroke in Indians. Methods : We studied 50 patients of nondiabetic acute ischaemic stroke within 24 hours of onset of symptoms for MA by dipstick urinalysis. Results: The incidence of MA was 68% (34 patients). Of all the traditional risk factors for stroke-age, male gender, hypertension, dyslipidaemia, smoking, obesity - only age of patients (>60 years) showed a positive correlation with the presence of MA (-<0.05). Patients with MA had more severe neurological deficit (Scandinavian Stroke Scale {SSS} < 30 vs. > 30; mean+S.D=24.3+8.66 vs. 30.3+10.3, p<0.03) and more severe depressed levels of consciousness {SSS < 4 vs. SSS > 6, 82.35 vs. 17.6, p<0.05). Conclusion: The incidence of MA in Indians with nondiabetic acute ischaemic stroke is significantly higher than that of western populations. Patients with MA in the first 24 hours after the onset of stroke have more severe neurological deficit and depressed levels of consciousness than patients without MA.