A concise and efficient synthesis of benzimidazo[1,2-c]quinazolines through CuI-catalyzed intramolecular N-arylations

A concise and efficient synthesis of benzimidazo[1,2-c]quinazolines through CuI-catalyzed intramolecular N-arylations

A series of functionalized benzimidazo[1,2-c]quinazoline derivatives was obtained in excellent yields under mild conditions through a CuI-catalyzed Ullmann N-arylation starting from easily available starting materials.

Bibliographic Details
Main Authors: Xinlong Pang, Chao Chen, Ming Li, Chanjuan Xi
Format: Article
Language:English
Published: Beilstein-Institut 2015-11-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
benzimidazo[1,2-c]quinazoline
(bromophenyl)iodonium salt
copper catalyst
o-cyanoaniline
quinazolin-4(3H)-imine
Ullmann N-arylation
Online Access:https://doi.org/10.3762/bjoc.11.258
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spelling doaj-499fb89fb471407ba4f637fba0e87e062021-02-02T09:04:45ZengBeilstein-InstitutBeilstein Journal of Organic Chemistry1860-53972015-11-011112365236910.3762/bjoc.11.2581860-5397-11-258A concise and efficient synthesis of benzimidazo[1,2-c]quinazolines through CuI-catalyzed intramolecular N-arylationsXinlong Pang0Chao Chen1Ming Li2Chanjuan Xi3Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology (Ministry of Education), Department of Chemistry, Tsinghua University, Beijing 100084, China, Tel: +86-10-62773684Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology (Ministry of Education), Department of Chemistry, Tsinghua University, Beijing 100084, China, Tel: +86-10-62773684College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao, 266042, ChinaKey Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology (Ministry of Education), Department of Chemistry, Tsinghua University, Beijing 100084, China, Tel: +86-10-62773684A series of functionalized benzimidazo[1,2-c]quinazoline derivatives was obtained in excellent yields under mild conditions through a CuI-catalyzed Ullmann N-arylation starting from easily available starting materials.https://doi.org/10.3762/bjoc.11.258benzimidazo[1,2-c]quinazoline(bromophenyl)iodonium saltcopper catalysto-cyanoanilinequinazolin-4(3H)-imineUllmann N-arylation
collection DOAJ
language English
format Article
sources DOAJ
author Xinlong Pang
Chao Chen
Ming Li
Chanjuan Xi
spellingShingle Xinlong Pang
Chao Chen
Ming Li
Chanjuan Xi
A concise and efficient synthesis of benzimidazo[1,2-c]quinazolines through CuI-catalyzed intramolecular N-arylations
Beilstein Journal of Organic Chemistry
benzimidazo[1,2-c]quinazoline
(bromophenyl)iodonium salt
copper catalyst
o-cyanoaniline
quinazolin-4(3H)-imine
Ullmann N-arylation
author_facet Xinlong Pang
Chao Chen
Ming Li
Chanjuan Xi
author_sort Xinlong Pang
title A concise and efficient synthesis of benzimidazo[1,2-c]quinazolines through CuI-catalyzed intramolecular N-arylations
title_short A concise and efficient synthesis of benzimidazo[1,2-c]quinazolines through CuI-catalyzed intramolecular N-arylations
title_full A concise and efficient synthesis of benzimidazo[1,2-c]quinazolines through CuI-catalyzed intramolecular N-arylations
title_fullStr A concise and efficient synthesis of benzimidazo[1,2-c]quinazolines through CuI-catalyzed intramolecular N-arylations
title_full_unstemmed A concise and efficient synthesis of benzimidazo[1,2-c]quinazolines through CuI-catalyzed intramolecular N-arylations
title_sort concise and efficient synthesis of benzimidazo[1,2-c]quinazolines through cui-catalyzed intramolecular n-arylations
publisher Beilstein-Institut
series Beilstein Journal of Organic Chemistry
issn 1860-5397
publishDate 2015-11-01
description A series of functionalized benzimidazo[1,2-c]quinazoline derivatives was obtained in excellent yields under mild conditions through a CuI-catalyzed Ullmann N-arylation starting from easily available starting materials.
topic benzimidazo[1,2-c]quinazoline
(bromophenyl)iodonium salt
copper catalyst
o-cyanoaniline
quinazolin-4(3H)-imine
Ullmann N-arylation
url https://doi.org/10.3762/bjoc.11.258
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AT chaochen aconciseandefficientsynthesisofbenzimidazo12cquinazolinesthroughcuicatalyzedintramolecularnarylations
AT mingli aconciseandefficientsynthesisofbenzimidazo12cquinazolinesthroughcuicatalyzedintramolecularnarylations
AT chanjuanxi aconciseandefficientsynthesisofbenzimidazo12cquinazolinesthroughcuicatalyzedintramolecularnarylations
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