Adult neural precursors isolated from post mortem brain yield mostly neurons: An erythropoietin-dependent process

Adult neural precursors isolated from post mortem brain yield mostly neurons: An erythropoietin-dependent process

This study was aimed at the isolation of neural precursor cells (NPCs) capable of resisting to a prolonged ischemic insult as this may occur at the site of traumatic and ischemic CNS injuries. Adult mice were anesthetized and then killed by cervical dislocation. The cadavers were maintained at room...

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Bibliographic Details
Main Authors: Giovanni Marfia, Laura Madaschi, Francesca Marra, Mauro Menarini, Daniele Bottai, Alessandro Formenti, Carmelo Bellardita, Anna Maria Di Giulio, Stephana Carelli, Alfredo Gorio
Format: Article
Language:English
Published: Elsevier 2011-07-01
Series:Neurobiology of Disease
Subjects:
Adult neural progenitors
Erythropoietin
Gene regulation
Hypoxia- inducible factor-1 (HIF-1)
mTOR
Neural plasticity
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996111000581

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