Host genetics predict clinical deterioration in HCV-related cirrhosis.

Host genetics predict clinical deterioration in HCV-related cirrhosis.

Single nucleotide polymorphisms (SNPs) in the epidermal growth factor (EGF, rs4444903), patatin-like phospholipase domain-containing protein 3 (PNPLA3, rs738409) genes, and near the interleukin-28B (IL28B, rs12979860) gene are linked to treatment response, fibrosis, and hepatocellular carcinoma (HCC...

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Bibliographic Details
Main Authors:	Lindsay Y King, Kara B Johnson, Hui Zheng, Lan Wei, Thomas Gudewicz, Yujin Hoshida, Kathleen E Corey, Tokunbo Ajayi, Nneka Ufere, Thomas F Baumert, Andrew T Chan, Kenneth K Tanabe, Bryan C Fuchs, Raymond T Chung
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2014-01-01
Series:	PLoS ONE
Online Access:	https://doi.org/10.1371/journal.pone.0114747

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