The Search for a Subtype-Selective PET Imaging Agent for the GABA Receptor Complex: Evaluation of the Radiotracer [C]ADO in Nonhuman Primates

The myriad physiological functions of γ-amino butyric acid (GABA) are mediated by the GABA-benzodiazepine receptor complex comprising of the GABA A , GABA B , and GABA C groups. The various GABA A subunits with region-specific distributions in the brain subserve different functional and physiologica...

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Main Authors: Shu-fei Lin PhD, Frederic Bois PhD, Daniel Holden BA, Nabeel Nabulsi PhD, Richard Pracitto MS, Hong Gao MS, Michael Kapinos BS, Jo-ku Teng BS, Anupama Shirali PhD, Jim Ropchan PhD, Richard E. Carson PhD, Charles S. Elmore PhD, Neil Vasdev PhD, Yiyun Huang PhD
Format: Article
Language:English
Published: Hindawi - SAGE Publishing 2017-09-01
Series:Molecular Imaging
Online Access:https://doi.org/10.1177/1536012117731258