Computational detection of significant variation in binding affinity across two sets of sequences with application to the analysis of replication origins in yeast

Computational detection of significant variation in binding affinity across two sets of sequences with application to the analysis of replication origins in yeast

<p>Abstract</p> <p>Background</p> <p>In analyzing the stability of DNA replication origins in <it>Saccharomyces cerevisiae </it>we faced the question whether one set of sequences is significantly enriched in the number and/or the quality of the matches of a...

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Bibliographic Details
Main Authors: Liachko Ivan, Bhaskar Anand, Garretson Jeffrey S, Gao Hong, Keich Uri, Donato Justin, Tye Bik K
Format: Article
Language:English
Published: BMC 2008-09-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/9/372

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