Computational detection of significant variation in binding affinity across two sets of sequences with application to the analysis of replication origins in yeast

<p>Abstract</p> <p>Background</p> <p>In analyzing the stability of DNA replication origins in <it>Saccharomyces cerevisiae </it>we faced the question whether one set of sequences is significantly enriched in the number and/or the quality of the matches of a...

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Bibliographic Details
Main Authors: Liachko Ivan, Bhaskar Anand, Garretson Jeffrey S, Gao Hong, Keich Uri, Donato Justin, Tye Bik K
Format: Article
Language:English
Published: BMC 2008-09-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/9/372