The Crystal Structure of the Drosophila Germline Inducer Oskar Identifies Two Domains with Distinct Vasa Helicase- and RNA-Binding Activities

The Crystal Structure of the Drosophila Germline Inducer Oskar Identifies Two Domains with Distinct Vasa Helicase- and RNA-Binding Activities

In many animals, the germ plasm segregates germline from soma during early development. Oskar protein is known for its ability to induce germ plasm formation and germ cells in Drosophila. However, the molecular basis of germ plasm formation remains unclear. Here, we show that Oskar is an RNA-binding...

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Bibliographic Details
Main Authors: Mandy Jeske, Matteo Bordi, Sebastian Glatt, Sandra Müller, Vladimir Rybin, Christoph W. Müller, Anne Ephrussi
Format: Article
Language:English
Published: Elsevier 2015-07-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124715006816

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