Adenovirus-mediated interleukin-12 gene transfer combined with <it>cytosine deaminase </it>followed by 5-fluorocytosine treatment exerts potent antitumor activity in Renca tumor-bearing mice

<p>Abstract</p> <p>Background</p> <p>Therapeutic gene transfer affords a clinically feasible and safe approach to cancer treatment but a more effective modality is needed to improve clinical outcomes. Combined transfer of therapeutic genes with different modes of action...

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Bibliographic Details
Main Authors: Kim Samyong, Yun Hwan-Jung, Yoo Jinsang, Cho Won-Kyung, Hwang Kyung-Sun, Im Dong-Soo
Format: Article
Language:English
Published: BMC 2005-05-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/5/51