Acyl-protein thioesterase 2 catalyzes the deacylation of peripheral membrane-associated GAP-43.

An acylation/deacylation cycle is necessary to maintain the steady-state subcellular distribution and biological activity of S-acylated peripheral proteins. Despite the progress that has been made in identifying and characterizing palmitoyltransferases (PATs), much less is known about the thioestera...

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Bibliographic Details
Main Authors: Vanesa M Tomatis, Alejandra Trenchi, Guillermo A Gomez, Jose L Daniotti
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-11-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21152083/pdf/?tool=EBI