Circulating Tumour Cell Numbers Correlate with Platelet Count and Circulating Lymphocyte Subsets in Men with Advanced Prostate Cancer: Data from the ExPeCT Clinical Trial (CTRIAL-IE 15-21)

Circulating Tumour Cell Numbers Correlate with Platelet Count and Circulating Lymphocyte Subsets in Men with Advanced Prostate Cancer: Data from the ExPeCT Clinical Trial (CTRIAL-IE 15-21)

Interactions between circulating tumour cells (CTCs) and platelets are thought to inhibit natural killer(NK)-cell-induced lysis. We attempted to correlate CTC numbers in men with advanced prostate cancer with platelet counts and circulating lymphocyte numbers. Sixty-one ExPeCT trial participants, di...

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Bibliographic Details
Main Authors: Brian Hayes, Lauren Brady, Gráinne Sheill, Anne-Marie Baird, Emer Guinan, Bryan Stanfill, Jean Dunne, Dean Holden, Tatjana Vlajnic, Orla Casey, Verena Murphy, John Greene, Emma H. Allott, Juliette Hussey, Fidelma Cahill, Mieke Van Hemelrijck, Nicola Peat, Lorelei A. Mucci, Moya Cunningham, Liam Grogan, Thomas Lynch, Rustom P. Manecksha, John McCaffrey, Dearbhaile M. O’Donnell, Orla Sheils, John J. O’Leary, Sarah Rudman, Ray McDermott, Stephen Finn
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Cancers
Subjects:
prostate cancer
circulating tumour cells
exercise
flow cytometry
platelets
inflammation
Online Access:https://www.mdpi.com/2072-6694/13/18/4690

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