The Glyoxalase System in Age-Related Diseases: Nutritional Intervention as Anti-Ageing Strategy

The Glyoxalase System in Age-Related Diseases: Nutritional Intervention as Anti-Ageing Strategy

The glyoxalase system is critical for the detoxification of advanced glycation end-products (AGEs). AGEs are toxic compounds resulting from the non-enzymatic modification of biomolecules by sugars or their metabolites through a process called glycation. AGEs have adverse effects on many tissues, pla...

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Bibliographic Details
Main Authors: Gemma Aragonès, Sheldon Rowan, Sarah G. Francisco, Elizabeth A. Whitcomb, Wenxin Yang, Giuliana Perini-Villanueva, Casper G. Schalkwijk, Allen Taylor, Eloy Bejarano
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Cells
Subjects:
glycative stress
glyoxalase system
aging
proteotoxicity
Online Access:https://www.mdpi.com/2073-4409/10/8/1852

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