BMP-2 induces versican and hyaluronan that contribute to post-EMT AV cushion cell migration.

BMP-2 induces versican and hyaluronan that contribute to post-EMT AV cushion cell migration.

Distal outgrowth and maturation of mesenchymalized endocardial cushions are critical morphogenetic events during post-EMT atrioventricular (AV) valvuloseptal morphogenesis. We explored the role of BMP-2 in the regulation of valvulogenic extracellular matrix (ECM) components, versican and hyaluronan...

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Bibliographic Details
Main Authors: Kei Inai, Jessica L Burnside, Stanley Hoffman, Bryan P Toole, Yukiko Sugi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3795687?pdf=render

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