Neuroprotective mechanisms of erythropoietin in a rat stroke model

Neuroprotective mechanisms of erythropoietin in a rat stroke model

This study was designed to investigate the indirect neuroprotective properties of recombinant human erythropoietin (rhEPO) pretreatment in a rat model of transient middle cerebral artery occlusion (MCAO).

Bibliographic Details
Main Authors: Juenemann Martin, Braun Tobias, Schleicher Nadine, Yeniguen Mesut, Schramm Patrick, Gerriets Tibo, Ritschel Nouha, Bachmann Georg, Obert Martin, Schoenburg Markus, Kaps Manfred, Tschernatsch Marlene
Format: Article
Language:English
Published: De Gruyter 2020-05-01
Series:Translational Neuroscience
Subjects:
neuroprotection
rat
recombinant human erythropoietin
transient focal cerebral ischemia
vascular disorders
craniectomy
Online Access:https://doi.org/10.1515/tnsci-2020-0008
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spelling doaj-494523cf69854b89a69c1a0d95ad6c9f2021-09-05T20:51:32ZengDe GruyterTranslational Neuroscience2081-69362020-05-01111485910.1515/tnsci-2020-0008tnsci-2020-0008Neuroprotective mechanisms of erythropoietin in a rat stroke modelJuenemann Martin0Braun Tobias1Schleicher Nadine2Yeniguen Mesut3Schramm Patrick4Gerriets Tibo5Ritschel Nouha6Bachmann Georg7Obert Martin8Schoenburg Markus9Kaps Manfred10Tschernatsch Marlene11Department of Neurology, Justus-Liebig-University Giessen, Klinikstrasse 33, 35392, Giessen, GermanyDepartment of Neurology, Justus-Liebig-University Giessen, Klinikstrasse 33, 35392, Giessen, GermanyHeart & Brain Research Group, Justus-Liebig-University Giessen and Kerckhoff Clinic, Benekestrasse 2-8, 61231, Bad Nauheim, GermanyDepartment of Neurology, Justus-Liebig-University Giessen, Klinikstrasse 33, 35392, Giessen, GermanyDepartment of Neurology, Justus-Liebig-University Giessen, Klinikstrasse 33, 35392, Giessen, GermanyDepartment of Neurology, Justus-Liebig-University Giessen, Klinikstrasse 33, 35392, Giessen, GermanyMax-Planck-Institute for Heart and Lung Research, Ludwigstraße 43, 61231, Bad Nauheim, GermanyDepartment of Radiology, Kerckhoff Clinic, 61231, Bad Nauheim, GermanyDepartment of Radiology, Justus-Liebig-University Giessen, Klinikstrasse 33, 35392, Giessen, GermanyDepartment of Cardiac Surgery, Kerckhoff Clinic, 61231, Bad Nauheim, GermanyDepartment of Neurology, Justus-Liebig-University Giessen, Klinikstrasse 33, 35392, Giessen, GermanyDepartment of Neurology, Justus-Liebig-University Giessen, Klinikstrasse 33, 35392, Giessen, GermanyThis study was designed to investigate the indirect neuroprotective properties of recombinant human erythropoietin (rhEPO) pretreatment in a rat model of transient middle cerebral artery occlusion (MCAO).https://doi.org/10.1515/tnsci-2020-0008neuroprotectionratrecombinant human erythropoietintransient focal cerebral ischemiavascular disorderscraniectomy
collection DOAJ
language English
format Article
sources DOAJ
author Juenemann Martin
Braun Tobias
Schleicher Nadine
Yeniguen Mesut
Schramm Patrick
Gerriets Tibo
Ritschel Nouha
Bachmann Georg
Obert Martin
Schoenburg Markus
Kaps Manfred
Tschernatsch Marlene
spellingShingle Juenemann Martin
Braun Tobias
Schleicher Nadine
Yeniguen Mesut
Schramm Patrick
Gerriets Tibo
Ritschel Nouha
Bachmann Georg
Obert Martin
Schoenburg Markus
Kaps Manfred
Tschernatsch Marlene
Neuroprotective mechanisms of erythropoietin in a rat stroke model
Translational Neuroscience
neuroprotection
rat
recombinant human erythropoietin
transient focal cerebral ischemia
vascular disorders
craniectomy
author_facet Juenemann Martin
Braun Tobias
Schleicher Nadine
Yeniguen Mesut
Schramm Patrick
Gerriets Tibo
Ritschel Nouha
Bachmann Georg
Obert Martin
Schoenburg Markus
Kaps Manfred
Tschernatsch Marlene
author_sort Juenemann Martin
title Neuroprotective mechanisms of erythropoietin in a rat stroke model
title_short Neuroprotective mechanisms of erythropoietin in a rat stroke model
title_full Neuroprotective mechanisms of erythropoietin in a rat stroke model
title_fullStr Neuroprotective mechanisms of erythropoietin in a rat stroke model
title_full_unstemmed Neuroprotective mechanisms of erythropoietin in a rat stroke model
title_sort neuroprotective mechanisms of erythropoietin in a rat stroke model
publisher De Gruyter
series Translational Neuroscience
issn 2081-6936
publishDate 2020-05-01
description This study was designed to investigate the indirect neuroprotective properties of recombinant human erythropoietin (rhEPO) pretreatment in a rat model of transient middle cerebral artery occlusion (MCAO).
topic neuroprotection
rat
recombinant human erythropoietin
transient focal cerebral ischemia
vascular disorders
craniectomy
url https://doi.org/10.1515/tnsci-2020-0008
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