The burden of pneumococcal disease in children less than 5 years of age in Abu Dhabi, United Arab Emirates

• Main Authors: Howidi Mohammad, Muhsin Haider, Rajah Jaishen
• Format: Article
• Language: English
• Published: King Faisal Specialist Hospital and Research Centre 2011-01-01
• Series: Annals of Saudi Medicine
• Online Access: http://www.saudiannals.net/article.asp?issn=0256-4947;year=2011;volume=31;issue=4;spage=356;epage=359;aulast=Howidi

<b>Background and Objective:</b> <i>Streptococcus pneumoniae</i> is a major cause of mortality and morbidity in both developing and industrialized countries, especially among young children and in both immunocompromised and immunocompetent individuals. It is implicated in both invasive (e.g. meningitis and septicemia) as well as noninvasive disease (community-acquired pneumonia and otitis media). The objective of the current study was to describe the overall epidemiology of both invasive and noninvasive pneumococcal disease in Abu Dhabi over a 5-year period. <b>Design and Setting:</b> Retrospective review of all pediatric (&#8804; 5 year old) pneumococcal disease admissions to Shaikh Khalifa Medical City (SKMC) and Mafraq Hospital in Abu Dhabi from 1 January 2001 till 31 December 2005.th <b>Methods</b>: We retrieved computerized data from the health information management systems (International Classification of Diseases, 9th Revision (ICD9) diagnosis codes) as well as manual surveillance in the laboratory record of pneumococcal isolates. <b>Results:</b> The incidence of invasive pneumococcal disease was 13.6/100&#8197;000 per year (95&#x0025; CI, 6.5-24.9) and the incidence of noninvasive pneumococcal disease was 172.5/100&#8197;000 per year (95&#x0025; CI, 143.8-205.2). The total incidence rate was 186.0/100&#8197;000 per year (95&#x0025; CI, 156.2-219.9). <b>Conclusion</b>: This epidemiological survey indicates that the incidence rates in the United Arab Emiratea are higher than in Western countries where conjugate pneumococcal vaccine has been introduced. This study is important as it documents the incidence of pneumococcal disease in the era before introduction of the conjugate pneumococcal vaccine and allows for future research to document the impact of a new vaccine considering the geographic variation of pneumococcal serotypes.