Role of Pannexin-1 hemichannels and purinergic receptors in the pathogenesis of human diseases

In the last decade several groups have determined the key role of hemichannels formed by pannexins or connexins, extracellular ATP and purinergic receptors in physiological and pathological conditions. Our work and the work of others, indicate that the opening of Pannexin-1 hemichannels and activati...

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Bibliographic Details
Main Authors: Stephani eVelasquez, Eliseo A Eugenin
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-03-01
Series:Frontiers in Physiology
Subjects:
HIV
ATP
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2014.00096/full