A clinical study of newly-diagnosed colorectal cancer over 2 years in a gastroenterology center in Iraq

Background and study aims: Colorectal cancer (CRC) is the most common gastrointestinal cancer and the third most commonly diagnosed malignancy affecting about one million individuals each year. The etiology for most cases of CRC appears to be related to environmental factors. This study to describe...

Full description

Bibliographic Details
Main Authors: Abdulhadi Alrubaie, Nawal Alkhalidi, Summar Abd-Alhusain
Format: Article
Language:English
Published: Thieme Revinter Publicações Ltda. 2019-07-01
Series:Journal of Coloproctology
Online Access:http://www.sciencedirect.com/science/article/pii/S2237936319300577
id doaj-493307b8be9f49cc9458551dbd65fa45
record_format Article
spelling doaj-493307b8be9f49cc9458551dbd65fa452021-07-02T14:02:29ZengThieme Revinter Publicações Ltda.Journal of Coloproctology2237-93632019-07-01393217222A clinical study of newly-diagnosed colorectal cancer over 2 years in a gastroenterology center in IraqAbdulhadi Alrubaie0Nawal Alkhalidi1Summar Abd-Alhusain2University of Baghdad, Alkindy College of Medicine, Baghdad, Iraq; Corresponding author.Ministry of Health, Gastroenterology Center, Baghdad, IraqKirkuk Medical College, Kirkuk, IraqBackground and study aims: Colorectal cancer (CRC) is the most common gastrointestinal cancer and the third most commonly diagnosed malignancy affecting about one million individuals each year. The etiology for most cases of CRC appears to be related to environmental factors. This study to describe the main characteristics of this malignancy regarding age, gender, and anatomical sub site distribution, as well as the main presenting symptoms in Iraqi patients. Patients and methods: Patients with newly-diagnosed CRC by colonoscopy findings and confirmed by histopathological examination of endoscopic colonic biopsies were studied. Results: Sixty three cases with a newly-diagnosed CRC were included in this study. There were 31 (49.2%) males and 32 (50.8%) females. CRC peaked in the 60–69 years old age group (p < 0.05), more than 60% were between 40 and 69 years old. Fresh bleeding per rectum was the most common symptom occurred in 48 (76.2%) patients; while the least common was weight loss (19%). The mean duration of symptoms before referral was 7.3 ± 12.6 months. The tumor sites of the CRC were the rectum and sigmoid region seen in 77.8% (p < 0.05), the rectum alone reported in 37 patients (58.7%); followed by sigmoid colon in 12 (19%) patients, cecum in 7 (11.1%) patients and the ascending colon seen in 2 (3.2%) patients. Conclusions: In this study CRC occurs in relatively younger age groups in comparison to studies in the developed countries with rectal cancer predominates of all colorectal cancers. Resumo: Contexto e objetivos do estudo: O câncer colorretal é a neoplasia gastrointestinal mais comum e o terceiro tumor maligno mais comumente diagnosticado, afetando cerca de um milhão de pessoas anualmente. A etiologia da maioria dos casos de câncer colorretal parece estar relacionada a fatores ambientais. Este estudo descreve as principais características dessa neoplasia quanto à idade, gênero e distribuição anatômica do subsite, bem como os principais sintomas observados em pacientes iraquianos. Pacientes e métodos: O estudo avaliou pacientes com câncer colorretal recém-diagnosticado por achados de colonoscopia e confirmados por exame histopatológico de biópsias endoscópicas do cólon. Resultados: O estudo incluiu 63 casos de pacientes com câncer colorretal recém-diagnosticado; 31 (49,2%) homens e 32 (50,8%) mulheres. O câncer colorretal atingiu o pico na faixa etária de 60 a 69 anos (p < 0,05); mais de 60% dos pacientes tinham entre 40 e 69 anos de idade. O sangramento retal fresco foi o sintoma mais comum em 48 (76,2%) pacientes; o sintoma menos comum foi a perda de peso (19%). A duração média dos sintomas antes do encaminhamento para especialista foi de 7,3 ± 12,6 meses. Os principais sítios tumorais do câncer colorretal foram a região do reto e sigmoide em 77,8% dos pacientes (p < 0,05) e o reto isolado em 37 pacientes (58,7%); seguido por cólon sigmoide em 12 pacientes (19%), ceco em sete (11,1%) e cólon ascendente em dois pacientes (3,2%). Conclusões: No presente estudo, o câncer colorretal foi observado em grupos etários relativamente mais jovens do que em estudos conduzidos em países desenvolvidos; a neoplasia retal foi o tipo de câncer colorretal mais comumente observado. Keywords: Colorectal cancer, Colonoscopy, Rectosegmoid cancer, Palavras-chave: Câncer colorretal, Colonoscopia, Câncer retossigmoidehttp://www.sciencedirect.com/science/article/pii/S2237936319300577
collection DOAJ
language English
format Article
sources DOAJ
author Abdulhadi Alrubaie
Nawal Alkhalidi
Summar Abd-Alhusain
spellingShingle Abdulhadi Alrubaie
Nawal Alkhalidi
Summar Abd-Alhusain
A clinical study of newly-diagnosed colorectal cancer over 2 years in a gastroenterology center in Iraq
Journal of Coloproctology
author_facet Abdulhadi Alrubaie
Nawal Alkhalidi
Summar Abd-Alhusain
author_sort Abdulhadi Alrubaie
title A clinical study of newly-diagnosed colorectal cancer over 2 years in a gastroenterology center in Iraq
title_short A clinical study of newly-diagnosed colorectal cancer over 2 years in a gastroenterology center in Iraq
title_full A clinical study of newly-diagnosed colorectal cancer over 2 years in a gastroenterology center in Iraq
title_fullStr A clinical study of newly-diagnosed colorectal cancer over 2 years in a gastroenterology center in Iraq
title_full_unstemmed A clinical study of newly-diagnosed colorectal cancer over 2 years in a gastroenterology center in Iraq
title_sort clinical study of newly-diagnosed colorectal cancer over 2 years in a gastroenterology center in iraq
publisher Thieme Revinter Publicações Ltda.
series Journal of Coloproctology
issn 2237-9363
publishDate 2019-07-01
description Background and study aims: Colorectal cancer (CRC) is the most common gastrointestinal cancer and the third most commonly diagnosed malignancy affecting about one million individuals each year. The etiology for most cases of CRC appears to be related to environmental factors. This study to describe the main characteristics of this malignancy regarding age, gender, and anatomical sub site distribution, as well as the main presenting symptoms in Iraqi patients. Patients and methods: Patients with newly-diagnosed CRC by colonoscopy findings and confirmed by histopathological examination of endoscopic colonic biopsies were studied. Results: Sixty three cases with a newly-diagnosed CRC were included in this study. There were 31 (49.2%) males and 32 (50.8%) females. CRC peaked in the 60–69 years old age group (p < 0.05), more than 60% were between 40 and 69 years old. Fresh bleeding per rectum was the most common symptom occurred in 48 (76.2%) patients; while the least common was weight loss (19%). The mean duration of symptoms before referral was 7.3 ± 12.6 months. The tumor sites of the CRC were the rectum and sigmoid region seen in 77.8% (p < 0.05), the rectum alone reported in 37 patients (58.7%); followed by sigmoid colon in 12 (19%) patients, cecum in 7 (11.1%) patients and the ascending colon seen in 2 (3.2%) patients. Conclusions: In this study CRC occurs in relatively younger age groups in comparison to studies in the developed countries with rectal cancer predominates of all colorectal cancers. Resumo: Contexto e objetivos do estudo: O câncer colorretal é a neoplasia gastrointestinal mais comum e o terceiro tumor maligno mais comumente diagnosticado, afetando cerca de um milhão de pessoas anualmente. A etiologia da maioria dos casos de câncer colorretal parece estar relacionada a fatores ambientais. Este estudo descreve as principais características dessa neoplasia quanto à idade, gênero e distribuição anatômica do subsite, bem como os principais sintomas observados em pacientes iraquianos. Pacientes e métodos: O estudo avaliou pacientes com câncer colorretal recém-diagnosticado por achados de colonoscopia e confirmados por exame histopatológico de biópsias endoscópicas do cólon. Resultados: O estudo incluiu 63 casos de pacientes com câncer colorretal recém-diagnosticado; 31 (49,2%) homens e 32 (50,8%) mulheres. O câncer colorretal atingiu o pico na faixa etária de 60 a 69 anos (p < 0,05); mais de 60% dos pacientes tinham entre 40 e 69 anos de idade. O sangramento retal fresco foi o sintoma mais comum em 48 (76,2%) pacientes; o sintoma menos comum foi a perda de peso (19%). A duração média dos sintomas antes do encaminhamento para especialista foi de 7,3 ± 12,6 meses. Os principais sítios tumorais do câncer colorretal foram a região do reto e sigmoide em 77,8% dos pacientes (p < 0,05) e o reto isolado em 37 pacientes (58,7%); seguido por cólon sigmoide em 12 pacientes (19%), ceco em sete (11,1%) e cólon ascendente em dois pacientes (3,2%). Conclusões: No presente estudo, o câncer colorretal foi observado em grupos etários relativamente mais jovens do que em estudos conduzidos em países desenvolvidos; a neoplasia retal foi o tipo de câncer colorretal mais comumente observado. Keywords: Colorectal cancer, Colonoscopy, Rectosegmoid cancer, Palavras-chave: Câncer colorretal, Colonoscopia, Câncer retossigmoide
url http://www.sciencedirect.com/science/article/pii/S2237936319300577
work_keys_str_mv AT abdulhadialrubaie aclinicalstudyofnewlydiagnosedcolorectalcancerover2yearsinagastroenterologycenteriniraq
AT nawalalkhalidi aclinicalstudyofnewlydiagnosedcolorectalcancerover2yearsinagastroenterologycenteriniraq
AT summarabdalhusain aclinicalstudyofnewlydiagnosedcolorectalcancerover2yearsinagastroenterologycenteriniraq
AT abdulhadialrubaie clinicalstudyofnewlydiagnosedcolorectalcancerover2yearsinagastroenterologycenteriniraq
AT nawalalkhalidi clinicalstudyofnewlydiagnosedcolorectalcancerover2yearsinagastroenterologycenteriniraq
AT summarabdalhusain clinicalstudyofnewlydiagnosedcolorectalcancerover2yearsinagastroenterologycenteriniraq
_version_ 1721328386295463936