Mast Cell Infiltration in Human Brain Metastases Modulates the Microenvironment and Contributes to the Metastatic Potential

Mast Cell Infiltration in Human Brain Metastases Modulates the Microenvironment and Contributes to the Metastatic Potential

Metastatic brain tumors continue to be a clinical problem, despite new therapeutic advances in cancer treatment. Brain metastases (BMs) are among the most common mass lesions in the brain that are resistant to chemotherapies, have a very poor prognosis, and currently lack any efficient diagnostic te...

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Bibliographic Details
Main Authors: Ananya Roy, Sylwia Libard, Holger Weishaupt, Ida Gustavsson, Lene Uhrbom, Göran Hesselager, Fredrik J. Swartling, Fredrik Pontén, Irina Alafuzoff, Elena Tchougounova
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-06-01
Series:Frontiers in Oncology
Subjects:
mast cell
brain metastases
IL-8
IL-10
matrix metalloprotease 2
vascular endothelial growth factor
Online Access:http://journal.frontiersin.org/article/10.3389/fonc.2017.00115/full

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