Inflammation-Induced Mucosal KYNU Expression Identifies Human Ileal Crohn’s Disease

Inflammation-Induced Mucosal KYNU Expression Identifies Human Ileal Crohn’s Disease

The widely varying therapeutic response of patients with inflammatory bowel disease (IBD) continues to raise questions regarding the unclarified heterogeneity of pathological mechanisms promoting disease progression. While biomarkers for the differentiation of Crohn’s disease (CD) versus ulcerative...

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Bibliographic Details
Main Authors: Meik Huhn, Martina Herrero San Juan, Balint Melcher, Caroline Dreis, Katrin G. Schmidt, Anja Schwiebs, Janet Collins, Josef M. Pfeilschifter, Michael Vieth, Jürgen Stein, Heinfried H. Radeke
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Journal of Clinical Medicine
Subjects:
kynurenine
kynureninase
3-hydroxyanthranilic acid
Crohn’s disease
tryptophan
IDO1
Online Access:https://www.mdpi.com/2077-0383/9/5/1360

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