Photocrosslinkable liver extracellular matrix hydrogels for the generation of 3D liver microenvironment models

Abstract Liver extracellular matrix (ECM)-based hydrogels have gained considerable interest as biomimetic 3D cell culture environments to investigate the mechanisms of liver pathology, metabolism, and toxicity. The preparation of current liver ECM hydrogels, however, is based on time-consuming therm...

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Bibliographic Details
Main Authors: Akhilandeshwari Ravichandran, Berline Murekatete, Denise Moedder, Christoph Meinert, Laura J. Bray
Format: Article
Language:English
Published: Nature Publishing Group 2021-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-94990-z