FOXM1 Inhibition in Ovarian Cancer Tissue Cultures Affects Individual Treatment Susceptibility Ex Vivo

FOXM1 Inhibition in Ovarian Cancer Tissue Cultures Affects Individual Treatment Susceptibility Ex Vivo

Diagnosis in an advanced state is a major hallmark of ovarian cancer and recurrence after first line treatment is common. With upcoming novel therapies, tumor markers that support patient stratification are urgently needed to prevent ineffective therapy. Therefore, the transcription factor FOXM1 is...

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Bibliographic Details
Main Authors: Luzie Brückner, Annika Reinshagen, Ngoc Anh Hoang, Anne Kathrin Höhn, Florian Lordick, Ingo Bechmann, Bahriye Aktas, Ivonne Nel, Sonja Kallendrusch
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Cancers
Subjects:
ovarian cancer
FOXM1
tissue culture
resistance
homologous recombination (HR)
susceptibility
Online Access:https://www.mdpi.com/2072-6694/13/5/956

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