A preliminary step of a novel strategy in suicide gene therapy with lentiviral vector

A preliminary step of a novel strategy in suicide gene therapy with lentiviral vector

Background: One of the challenges in lentiviral vector-based suicide gene therapy by toxin or apoptosis-inducing genes is death of packaging cells. Therefore, the process of production of these lentiviral particles would be stopped in this step. We proposed that insertion of a reverse promoter betwe...

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Bibliographic Details
Main Authors: Jahan Afrooz Ghanbari, Mansoor Salehi, Arezoo Karam Zadeh, Sedigheh Momen Zadeh, Vahid Bahram Beigi, Hossein Khan Ahmad, Behzad Mahaki, Mina Beiraghdar
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2014-01-01
Series:Advanced Biomedical Research
Subjects:
Apoptosis-inducing genes
CMV promoter
gene therapy
GFP
lentiviral vectors
RΔU3 sequence
Online Access:http://www.advbiores.net/article.asp?issn=2277-9175;year=2014;volume=3;issue=1;spage=7;epage=7;aulast=Ghanbari

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http://www.advbiores.net/article.asp?issn=2277-9175;year=2014;volume=3;issue=1;spage=7;epage=7;aulast=Ghanbari

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