Cytomegalovirus infection in pediatric rheumatic diseases: a review

<p>Abstract</p> <p>Human cytomegalovirus (HCMV) is familiar to pediatric rheumatologists mainly as a cause of opportunistic disease in pharmacologically immune suppressed patients. However, HCMV also has a variety of immuno-modulatory effects, through which it may influence the cou...

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Bibliographic Details
Main Authors: Wolf Dana G, Eisenstein Eli M
Format: Article
Language:English
Published: BMC 2010-05-01
Series:Pediatric Rheumatology Online Journal
Online Access:http://www.ped-rheum.com/content/8/1/17
Description
Summary:<p>Abstract</p> <p>Human cytomegalovirus (HCMV) is familiar to pediatric rheumatologists mainly as a cause of opportunistic disease in pharmacologically immune suppressed patients. However, HCMV also has a variety of immuno-modulatory effects, through which it may influence the course of rheumatic conditions. In this article we discuss the interplay between HCMV and the immune system, and review the clinical manifestations, diagnosis, and treatment of HCMV infection in children with rheumatic disease.</p>
ISSN:1546-0096