Nα-1, 3-Benzenedicarbonyl-Bis-(Amino Acid) and Dipeptide Candidates: Synthesis, Cytotoxic, Antimicrobial and Molecular Docking Investigation

Nα-1, 3-Benzenedicarbonyl-Bis-(Amino Acid) and Dipeptide Candidates: Synthesis, Cytotoxic, Antimicrobial and Molecular Docking Investigation

Ahmed M Naglah,1,2 Gaber O Moustafa,2 Ahmed A Elhenawy,3,4 Marwa M Mounier,5 Heba El-Sayed,6 Mohamed A Al-Omar,1 Abdulrahman A Almehizia,1,7 Mashooq A Bhat7 1Department of Pharmaceutical Chemistry, Drug Exploration & Development Chair (DEDC), College of Pharmacy, King Saud University, Riyadh...

Full description

Bibliographic Details
Main Authors:	Naglah AM, Moustafa GO, Elhenawy AA, Mounier MM, El-Sayed H, Al-Omar MA, Almehizia AA, Bhat MA
Format:	Article
Language:	English
Published:	Dove Medical Press 2021-03-01
Series:	Drug Design, Development and Therapy
Subjects:	anticancer antimicrobial activity linear peptides nα-1 3-benzenedicarbonyl -bis-peptides molecular docking
Online Access:	https://www.dovepress.com/nalpha-1-3-benzenedicarbonyl-bis-amino-acid-and-dipeptide-candidates-s-peer-reviewed-article-DDDT

Similar Items

Synthesis, Docking, Computational Studies, and Antimicrobial Evaluations of New Dipeptide Derivatives Based on Nicotinoylglycylglycine Hydrazide
by: Hemat S. Khalaf, et al.
Published: (2020-08-01)

Synthesis, comparative docking, and pharmacological activity of naproxen amino acid derivatives as possible anti-inflammatory and analgesic agents
by: Elhenawy AA, et al.
Published: (2019-05-01)

In vitro anticancer potentiality and molecular modelling study of novel amino acid derivatives based on N1,N3-bis-(1-hydrazinyl-1-oxopropan-2-yl) isophthalamide
by: Asmaa F. Kassem, et al.
Published: (2019-01-01)

Synthesis, molecular docking and biological evaluation of bis-pyrimidine Schiff base derivatives
by: Sanjiv Kumar, et al.
Published: (2017-09-01)

Synthesis, molecular docking and biological evaluation of bis-pyrimidine Schiff base derivatives
by: Kumar, S., et al.
Published: (2017)

Synthesis, Characterization, In Vitro Anticancer Potentiality, and Antimicrobial Activities of Novel Peptide–Glycyrrhetinic-Acid-Based Derivatives
by: Gaber O. Moustafa, et al.
Published: (2021-07-01)

A protocol for CABS-dock protein–peptide docking driven by side-chain contact information
by: Mateusz Kurcinski, et al.
Published: (2017-08-01)

Improved Modeling of Peptide-Protein Binding Through Global Docking and Accelerated Molecular Dynamics Simulations
by: Jinan Wang, et al.
Published: (2019-10-01)

Modeling EphB4-EphrinB2 protein–protein interaction using flexible docking of a short linear motif
by: Maciej Pawel Ciemny, et al.
Published: (2017-08-01)

Identification of renin inhibitors peptides from amaranth proteins by docking protocols
by: Agustina E. Nardo, et al.
Published: (2020-01-01)

CancerGram: An Effective Classifier for Differentiating Anticancer from Antimicrobial Peptides
by: Michał Burdukiewicz, et al.
Published: (2020-10-01)

Physicochemical characterisation, molecular docking, and drug-likeness evaluation of hypotensive peptides encrypted in flaxseed proteome
by: Dawei Ji, et al.
Published: (2020-11-01)

In Silico Peptide Ligation: Iterative Residue Docking and Linking as a New Approach to Predict Protein-Peptide Interactions
by: Julien Diharce, et al.
Published: (2019-04-01)

Using parallelized incremental meta-docking can solve the conformational sampling issue when docking large ligands to proteins
by: Didier Devaurs, et al.
Published: (2019-09-01)

Benchmarking of different molecular docking methods for protein-peptide docking
by: Piyush Agrawal, et al.
Published: (2019-02-01)

Development and testing of liposome encapsulated cyclic dipeptides
by: Kilian, Gareth
Published: (2011)

Molecular Dynamics Scoring of Protein–Peptide Models Derived from Coarse-Grained Docking
by: Mateusz Zalewski, et al.
Published: (2021-05-01)

Peptides: A new class of anticancer drugs
by: Ryszard Smolarczyk, et al.
Published: (2009-07-01)

Paper Synthesis, Cytotoxicity and Apoptosis Induction in Human Tumor Cells by Galaxamide and Its Analogues
by: Xi Xiao, et al.
Published: (2014-08-01)

A Review for Antimicrobial Peptides with Anticancer Properties: Re-purposing of Potential Anticancer Agents
by: Cuiyu Zhong, et al.
Published: (2021-01-01)

Développements HPC pour une nouvelle méthode de docking inverse : applications aux protéines matricielles.
by: Vasseur, Romain
Published: (2015)

Effects of Rationally Designed Physico-Chemical Variants of the Peptide PuroA on Biocidal Activity towards Bacterial and Mammalian Cells
by: Nadin Shagaghi, et al.
Published: (2020-11-01)

Antiviral peptides against the main protease of SARS-CoV-2: A molecular docking and dynamics study
by: Shafi Mahmud, et al.
Published: (2021-09-01)

Antimicrobial Peptides as Anticancer Agents: Functional Properties and Biological Activities
by: Anna Lucia Tornesello, et al.
Published: (2020-06-01)

PeptoGrid—Rescoring Function for AutoDock Vina to Identify New Bioactive Molecules from Short Peptide Libraries
by: Arthur O. Zalevsky, et al.
Published: (2019-01-01)

5-(Thiophen-2-yl)-1,3,4-thiadiazole derivatives: synthesis, molecular docking and in vitro cytotoxicity evaluation as potential anticancer agents
by: Gomha SM, et al.
Published: (2018-05-01)

Recent Advances in Small Peptides of Marine Origin in Cancer Therapy
by: Qi-Ting Zhang, et al.
Published: (2021-02-01)

LFB: A Novel Antimicrobial Brevinin-Like Peptide from the Skin Secretion of the Fujian Large Headed Frog, <i>Limnonectes fujianensi</i>
by: Bin Li, et al.
Published: (2019-06-01)

Biomedical Relevance of Novel Anticancer Peptides in the Sensitive Treatment of Cancer
by: Olalekan Olanrewaju Bakare, et al.
Published: (2021-07-01)

Synthesis, Cytotoxicity Evaluation and Molecular Docking Studyof <i>N</i>-Phenylpyrazoline Derivatives
by: Artania Adnin Tri Suma, et al.
Published: (2019-08-01)

Self-Assembly, Characterization, and Cytotoxicity Studies of a Camptothecin-Dipeptide Library
by: Neidrich, Keisha L.
Published: (2016)

Whey-Derived Peptides Interactions with ACE by Molecular Docking as a Potential Predictive Tool of Natural ACE Inhibitors
by: Yara Chamata, et al.
Published: (2020-01-01)

P1′ Residue-Oriented Virtual Screening for Potent and Selective Phosphinic (Dehydro) Dipeptide Inhibitors of Metallo-Aminopeptidases
by: Michał Talma, et al.
Published: (2020-04-01)

MDA-MB-231 Breast Cancer Cells Resistant to Pleurocidin-Family Lytic Peptides Are Chemosensitive and Exhibit Reduced Tumor-Forming Capacity
by: Ashley L. Hilchie, et al.
Published: (2020-08-01)

Peptides Derived from (RRWQWRMKKLG)<sub>2-</sub>K-<i>Ahx</i> Induce Selective Cellular Death in Breast Cancer Cell Lines through Apoptotic Pathway
by: Diego Sebastián Insuasty-Cepeda, et al.
Published: (2020-06-01)

To What Extent Do Fluorophores Bias the Biological Activity of Peptides? A Practical Approach Using Membrane-Active Peptides as Models
by: Marco Cavaco, et al.
Published: (2020-09-01)

Erratum: To What Extent Do Fluorophores Bias the Biological Activity of Peptides? A Practical Approach Using Membrane-Active Peptides as Models
by: Frontiers Production Office
Published: (2020-11-01)

An Overview of Antimicrobial Peptides as Anticancer Agents
by: Ali Ganji, et al.
Published: (2019-09-01)

Recent Advances and Trends in Chemical CPP–Drug Conjugation Techniques
by: Félix Gayraud, et al.
Published: (2021-03-01)

Ib-M6 Antimicrobial Peptide: Antibacterial Activity against Clinical Isolates of <i>Escherichia coli</i> and Molecular Docking
by: J. M. Flórez-Castillo, et al.
Published: (2020-02-01)

Cannot write session to /tmp/vufind_sessions/sess_52lbqntavdspn6jgt3n19c6i3n