Increased Degradation Rates in the Components of the Mitochondrial Oxidative Phosphorylation Chain in the Cerebellum of Old Mice

Increased Degradation Rates in the Components of the Mitochondrial Oxidative Phosphorylation Chain in the Cerebellum of Old Mice

Brain structures differ in the magnitude of age-related neuron loss with the cerebellum being more affected. An underlying cause could be an age-related decline in mitochondrial bioenergetics. Successful aging of mitochondria reflects a balanced turnover of proteins involved in mitochondrial biogene...

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Bibliographic Details
Main Authors: Aurel Popa-Wagner, Raluca E. Sandu, Coman Cristin, Adriana Uzoni, Kevin A. Welle, Jennifer R. Hryhorenko, Sina Ghaemmaghami
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-02-01
Series:Frontiers in Aging Neuroscience
Subjects:
aging
mice
cerebellum
mitochondria
proteins
turnover
Online Access:http://journal.frontiersin.org/article/10.3389/fnagi.2018.00032/full

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