The biology of how circumcision reduces HIV susceptibility: broader implications for the prevention field

The biology of how circumcision reduces HIV susceptibility: broader implications for the prevention field

Abstract Circumcision reduces heterosexual HIV-1 acquisition in men by at least 60%. However, the biological mechanisms by which circumcision is protective remain incompletely understood. We test the hypothesis that the sub-preputial microenvironment created by the foreskin drives immune activation...

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Bibliographic Details
Main Authors: Jessica L. Prodger, Rupert Kaul
Format: Article
Language:English
Published: BMC 2017-09-01
Series:AIDS Research and Therapy
Subjects:
HIV-1
T-cells
Chemokines
Microbiome
Circumcision
Foreskin
Online Access:http://link.springer.com/article/10.1186/s12981-017-0167-6

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http://link.springer.com/article/10.1186/s12981-017-0167-6

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