A Unique GSK-3β inhibitor B10 Has a Direct Effect on Aβ, Targets Tau and Metal Dyshomeostasis, and Promotes Neuronal Neurite Outgrowth

A Unique GSK-3β inhibitor B10 Has a Direct Effect on Aβ, Targets Tau and Metal Dyshomeostasis, and Promotes Neuronal Neurite Outgrowth

Due to the complicated pathogenesis of Alzheimer’s disease (AD), the development of multitargeted agents to simultaneously interfere with multiple pathological processes of AD is a potential choice. Glycogen synthase kinase-3β (GSK-3β) plays a vital role in the AD patholo...

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Bibliographic Details
Main Authors: Xiao-Long Shi, Ning Yan, Ying-Jie Cui, Zhao-Peng Liu
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Cells
Subjects:
alzheimer’s disease
aβ
gsk-3β inhibitor
tau
metal dyshomeostasis
neurite outgrowth
Online Access:https://www.mdpi.com/2073-4409/9/3/649

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