VE-cadherin-independent cancer cell incorporation into the vascular endothelium precedes transmigration.

Metastasis is accountable for 90% of cancer deaths. During metastasis, tumor cells break away from the primary tumor, enter the blood and the lymph vessels, and use them as highways to travel to distant sites in the body to form secondary tumors. Cancer cell migration through the endothelium and int...

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Bibliographic Details
Main Authors: Susan M Hamilla, Kimberly M Stroka, Helim Aranda-Espinoza
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4183660?pdf=render