Chromofungin regulates autophagy flux to improve lung tissue inflammation in septic mice

Chromofungin regulates autophagy flux to improve lung tissue inflammation in septic mice

Objective To investigate the regulative role of chromogranin A derived polypeptide CGA47-66 (chromofungin, CHR) on autophagy flux and determine its effect on inflammatory injury in the lung tissue of septic mice. Methods C57BL/6 mice were inflicted by intraperitoneal administration of 10 mg/kg lipop...

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Bibliographic Details
Main Authors: KANG Shengnan, LIU Shuke, LIU Xian, WANG Fenglin, ZHOU Wushuang, CHEN Xiaoying, ZHANG Dan
Format: Article
Language:zho
Published: Editorial Office of Journal of Third Military Medical University 2021-07-01
Series:Di-san junyi daxue xuebao
Subjects:
chromofungin
sepsis
acute lung injury
autophagy flux
inflammation
Online Access:http://aammt.tmmu.edu.cn/Upload/rhtml/202102051.htm

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