Integrated Genomic and Metabolomic Approach to the Discovery of Potential Anti-Quorum Sensing Natural Products from Microbes Associated with Marine Samples from Singapore

Integrated Genomic and Metabolomic Approach to the Discovery of Potential Anti-Quorum Sensing Natural Products from Microbes Associated with Marine Samples from Singapore

With 70% of the Earth’s surface covered in water, the marine ecosystem offers immense opportunities for drug discovery and development. Due to the decreasing rate of novel natural product discovery from terrestrial sources in recent years, many researchers are beginning to look seaward for...

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Bibliographic Details
Main Authors: Ji Fa Marshall Ong, Hui Chin Goh, Swee Cheng Lim, Li Mei Pang, Joyce Seow Fong Chin, Koh Siang Tan, Zhao-Xun Liang, Liang Yang, Evgenia Glukhov, William H. Gerwick, Lik Tong Tan
Format: Article
Language:English
Published: MDPI AG 2019-01-01
Series:Marine Drugs
Subjects:
marine bacteria
marine sponges
anti-quorum sensing
molecular network
biosynthetic gene clusters
Online Access:https://www.mdpi.com/1660-3397/17/1/72

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