Necrotizing Histiocytic Lymphadenitis: Report of two cases (Kikuchi-Fujimoto disease)

Kikuchi-Fujimoto disease is a necrotizing Lymphadenitis with benign self-limit process in young women with fever, cervical lymphadenopathy and increased ESR with leukopenia. In this report we introduce 2 females with Kikuchi-Fujimoto disease. The first patient was a 31 years old lady with fever and...

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Bibliographic Details
Main Authors: M.Sharbatdaran (MD), Sh.Shefaee (MD), G.Joghataie (M.D)
Format: Article
Language:fas
Published: Golestan University of Medical Sciences 2004-09-01
Series:مجله دانشگاه علوم پزشکی گرگان
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Online Access:http://goums.ac.ir/journal/browse.php?a_code=A-10-1-212&slc_lang=en&sid=1
Description
Summary:Kikuchi-Fujimoto disease is a necrotizing Lymphadenitis with benign self-limit process in young women with fever, cervical lymphadenopathy and increased ESR with leukopenia. In this report we introduce 2 females with Kikuchi-Fujimoto disease. The first patient was a 31 years old lady with fever and unilateral cervical lymphadenopathy weight loss from 20 days age. In paraclinical findings ESR=50 mm/hr Hb=10 gr/dl. WBC count was 5300/µl bone marrow aspiration and biopsy with lymph node was done. The histopathologic diagnosis was Kikuchi-Fujimoto (Necrotizing Lymphadenitis). The 2nd patient was a lady with 35 years old and painful neck mass (Behind the sterno-clido mastoid) from 1.5-month age with fever and chill. In paraclinical findings ESR=52 mm/hr WBC 5500/µl, CRP++ lymph node biopsy was done the histopathologic diagnosis was Kikuchi-Fujimoto necrotizing Lymphadenitis. Therefore Kikuchi disease is a important differential diagnosis in young patients especially women with cervical lymphadenopathy and fever (FUO).
ISSN:1562-4765
2008-4080