TUFT1 Promotes Triple Negative Breast Cancer Metastasis, Stemness, and Chemoresistance by Up-Regulating the Rac1/β-Catenin Pathway

TUFT1 Promotes Triple Negative Breast Cancer Metastasis, Stemness, and Chemoresistance by Up-Regulating the Rac1/β-Catenin Pathway

Objectives: Triple negative breast cancer (TNBC) is a subtype of breast cancer with stronger invasion and metastasis, but its specific mechanism of action is still unclear. Tuft1 plays an important regulatory role in the survival of breast cancer cells; however, its role in regulating TNBC metastati...

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Bibliographic Details
Main Authors: Weiguang Liu, Guanglei Chen, Lisha Sun, Yue Zhang, Jianjun Han, Yuna Dai, Jianchao He, Sufang Shi, Bo Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Oncology
Subjects:
triple negative breast cancer (TNBC)
TUFT1
Rac1
metastasis
stemness
chemoresistance
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.00617/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2019.00617/full

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