The prototype HIV-1 maturation inhibitor, bevirimat, binds to the CA-SP1 cleavage site in immature Gag particles

The prototype HIV-1 maturation inhibitor, bevirimat, binds to the CA-SP1 cleavage site in immature Gag particles

<p>Abstract</p> <p>Background</p> <p>Bevirimat, the prototype Human Immunodeficiency Virus type 1 (HIV-1) maturation inhibitor, is highly potent in cell culture and efficacious in HIV-1 infected patients. In contrast to inhibitors that target the active site of the vira...

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Bibliographic Details
Main Authors: Nguyen Albert T, Feasley Christa L, Jackson Ken W, Nitz Theodore J, Salzwedel Karl, Air Gillian M, Sakalian Michael
Format: Article
Language:English
Published: BMC 2011-12-01
Series:Retrovirology
Online Access:http://www.retrovirology.com/content/8/1/101

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