A UPLC/DAD method for simultaneous determination of empagliflozin and three related substances in spiked human plasma

A UPLC/DAD method for simultaneous determination of empagliflozin and three related substances in spiked human plasma

Abstract A simple, rapid and sensitive ultrahigh performance liquid chromatographic method was developed for the determination of the anti-diabetic drug: empagliflozin (EMPA) and three related substances in spiked human plasma, using dapagliflozin (DAPA) as an internal standard and tetrahydrofuran a...

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Bibliographic Details
Main Authors: Mokhtar M. Mabrouk, Suzan M. Soliman, Heba M. El-Agizy, Fotouh R. Mansour
Format: Article
Language:English
Published: BMC 2019-07-01
Series:BMC Chemistry
Subjects:
Empagliflozin
Related substances
UPLC
Spiked human plasma
THF protein precipitation
Online Access:http://link.springer.com/article/10.1186/s13065-019-0604-9

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