Aging-related decline in the induction of Nrf2-regulated antioxidant genes in human bronchial epithelial cells

Evidence from animal studies suggests that stress-induced increases in Nrf2-regulated antioxidant gene expression, a critical mechanism of cellular protection, declines with aging. This study examined whether this also occurs in humans. We measured the basal and inducible levels of Nrf2-regulated an...

Full description

Bibliographic Details
Main Authors: Lulu Zhou, Hongqiao Zhang, Kelvin J.A. Davies, Henry Jay Forman
Format: Article
Language:English
Published: Elsevier 2018-04-01
Series:Redox Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231717306067