In vivo evidence for platelet-induced physiological angiogenesis by a COX driven mechanism.

We sought to determine a role for platelets in in vivo angiogenesis, quantified by changes in the capillary to fibre ratio (C:F) of mouse skeletal muscle, utilising two distinct forms of capillary growth to identify differential effects. Capillary sprouting was induced by muscle overload, and longit...

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Bibliographic Details
Main Authors: Ian M Packham, Steve P Watson, Roy Bicknell, Stuart Egginton
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4169573?pdf=render