Dissecting nucleosome free regions by a segmental semi-Markov model.

BACKGROUND: Nucleosome free regions (NFRs) play important roles in diverse biological processes including gene regulation. A genome-wide quantitative portrait of each individual NFR, with their starting and ending positions, lengths, and degrees of nucleosome depletion is critical for revealing the...

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Bibliographic Details
Main Authors: Wei Sun, Wei Xie, Feng Xu, Michael Grunstein, Ker-Chau Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2648986?pdf=render