Nicotine upregulates ACE2 expression and increases competence for SARS-CoV-2 in human pneumocytes

Nicotine upregulates ACE2 expression and increases competence for SARS-CoV-2 in human pneumocytes

The coronavirus disease 2019 (COVID-19) pandemic has a variable degree of severity according to underlying comorbidities and life-style. Several research groups have reported an association between cigarette smoking and increased severity of COVID-19. The exact mechanism of action is largely unclear...

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Bibliographic Details
Main Authors:	Fabrizio Maggi, Alfredo Rosellini, Pietro Giorgio Spezia, Daniele Focosi, Lisa Macera, Michele Lai, Mauro Pistello, Antonio de Iure, Carlo Tomino, Stefano Bonassi, Patrizia Russo
Format:	Article
Language:	English
Published:	European Respiratory Society 2021-04-01
Series:	ERJ Open Research
Online Access:	http://openres.ersjournals.com/content/7/2/00713-2020.full

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