Protective effect of asiaticoside on radiation-induced proliferation inhibition and DNA damage of fibroblasts and mice death

Protective effect of asiaticoside on radiation-induced proliferation inhibition and DNA damage of fibroblasts and mice death

Radiation-induced injuries (RII) mainly result from reactive oxygen species (ROS), which are harmful compounds that can damage DNA. Asiaticoside (AC), one of the main functional components extracted from Centella asiatica, has potent pharmacological effects such as anti-inflammatory and anti-oxidant...

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Bibliographic Details
Main Authors: Shen Haiyan, Zhu Fei, Li Jinsheng, Tang Songjia, Zhang Yale, Zhang Jufang
Format: Article
Language:English
Published: De Gruyter 2020-04-01
Series:Open Life Sciences
Subjects:
asiaticoside (ac)
radiation-induced injuries (rii)
antioxidant
dna damage
radio-protective
Online Access:https://doi.org/10.1515/biol-2020-0015
Description
Summary:Radiation-induced injuries (RII) mainly result from reactive oxygen species (ROS), which are harmful compounds that can damage DNA. Asiaticoside (AC), one of the main functional components extracted from Centella asiatica, has potent pharmacological effects such as anti-inflammatory and anti-oxidant activity. However, its role in RII remains unclear.
ISSN:2391-5412

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