BMPs direct sensory interneuron identity in the developing spinal cord using signal-specific not morphogenic activities

BMPs direct sensory interneuron identity in the developing spinal cord using signal-specific not morphogenic activities

The Bone Morphogenetic Protein (BMP) family reiteratively signals to direct disparate cellular fates throughout embryogenesis. In the developing dorsal spinal cord, multiple BMPs are required to specify sensory interneurons (INs). Previous studies suggested that the BMPs act as concentration-depende...

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Bibliographic Details
Main Authors: Madeline G Andrews, Lorenzo M del Castillo, Eliana Ochoa-Bolton, Ken Yamauchi, Jan Smogorzewski, Samantha J Butler
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-09-01
Series:eLife
Subjects:
bone morphogenetic proteins
spinal cord
patterning
cell fate
neurons
morphogen
Online Access:https://elifesciences.org/articles/30647

Internet

https://elifesciences.org/articles/30647

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