Role of hypoxia in cancer therapy by regulating the tumor microenvironment

Role of hypoxia in cancer therapy by regulating the tumor microenvironment

Abstract Aim Clinical resistance is a complex phenomenon in major human cancers involving multifactorial mechanisms, and hypoxia is one of the key components that affect the cellular expression program and lead to therapy resistance. The present study aimed to summarize the role of hypoxia in cancer...

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Bibliographic Details
Main Authors: Xinming Jing, Fengming Yang, Chuchu Shao, Ke Wei, Mengyan Xie, Hua Shen, Yongqian Shu
Format: Article
Language:English
Published: BMC 2019-11-01
Series:Molecular Cancer
Subjects:
Cancer therapy
Chemotherapy
Drug resistance
Hypoxia
Tumor microenvironment
Online Access:http://link.springer.com/article/10.1186/s12943-019-1089-9

Internet

http://link.springer.com/article/10.1186/s12943-019-1089-9

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