The effects of the miR-21/SMAD7/TGF-β pathway on Th17 cell differentiation in COPD

The effects of the miR-21/SMAD7/TGF-β pathway on Th17 cell differentiation in COPD

Abstract Chronic obstructive pulmonary disease (COPD) is a complex disease with multiple etiologies, while smoking is the most established one. The present study investigated the modulation of T-helper 17 (Th17) cell differentiation by the miR-21/Smad7/TGF-β pathway, and their roles in COPD. Lung ti...

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Bibliographic Details
Main Authors:	Shengyang He, Shenghua Sun, Junjuan Lu, Lili Chen, Xiang Mei, Liqiu Li, Zhengpeng Zeng, Mubin Zhong, Lihua Xie
Format:	Article
Language:	English
Published:	Nature Publishing Group 2021-03-01
Series:	Scientific Reports
Online Access:	https://doi.org/10.1038/s41598-021-85637-0

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