Cyclical aggregation extends in vitro expansion potential of human mesenchymal stem cells

Abstract Mesenchymal stem cell (MSC)-based therapy has shown great promises in various animal disease models. However, this therapeutic potency has not been well claimed when applied to human clinical trials. This is due to both the availability of MSCs at the time of administration and lack of viab...

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Bibliographic Details
Main Authors: Brent M. Bijonowski, Xuegang Yuan, Richard Jeske, Yan Li, Samuel C. Grant
Format: Article
Language:English
Published: Nature Publishing Group 2020-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-77288-4