Ganoderma lucidum Immune Modulator Protein rLZ-8 Could Prevent and Reverse Bone Loss in Glucocorticoids-Induced Osteoporosis Rat Model

Immune modulation has been recognized as an effective anti-osteoporosis strategy since the pivotal role of the RANK/RANKL/OPG signaling in bone metabolism and remodeling was discovered. To investigate the potential preventive and/or therapeutic effects of immune modulator protein Ling Zhi-8 (LZ-8) o...

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Bibliographic Details
Main Authors: Yong Yang, Tian Yu, Huan Tang, Zhihui Ren, Qianwen Li, Juan Jia, Hongyu Chen, Jun Fu, Shengchen Ding, Qiang Hao, Dan Xu, Liping Song, Bo Sun, Fei Sun, Jin Pei
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.00731/full