Drug persistence and need for dose intensification to adalimumab therapy; the importance of therapeutic drug monitoring in inflammatory bowel diseases

Drug persistence and need for dose intensification to adalimumab therapy; the importance of therapeutic drug monitoring in inflammatory bowel diseases

Abstract Background Therapeutic drug monitoring (TDM) aid therapeutic decision making in patients with inflammatory bowel disease (IBD) who lose response to anti-TNF therapy. Our aim was to evaluate the frequency and predictive factors of loss of response (LOR) to adalimumab using TDM in IBD patient...

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Bibliographic Details
Main Authors: Lorant Gonczi, Zsuzsanna Kurti, Mariann Rutka, Zsuzsanna Vegh, Klaudia Farkas, Barbara D. Lovasz, Petra A. Golovics, Krisztina B. Gecse, Balazs Szalay, Tamas Molnar, Peter L. Lakatos
Format: Article
Language:English
Published: BMC 2017-08-01
Series:BMC Gastroenterology
Subjects:
Adalimumab
Therapeutic drug monitoring
Inflammatory bowel diseases
Loss of response
Online Access:http://link.springer.com/article/10.1186/s12876-017-0654-1

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