Radioprotective effect of lidocaine on neurotransmitter agonist-induced secretion in irradiated salivary glands.

BACKGROUND: Previously we verified the radioprotective effect of lidocaine on the function and ultrastructure of salivary glands in rabbits. However, the underlying mechanism of lidocaine's radioprotective effect is unknown. We hypothesized that lidocaine, as a membrane stabilization agent, has...

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Bibliographic Details
Main Authors: Yu-xiong Su, Geza A Benedek, Peter Sieg, Gui-qing Liao, Andreas Dendorfer, Birgit Meller, Dirk Rades, Matthias Klinger, Samer G Hakim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3612107?pdf=render