Kv7 channels can function without constitutive calmodulin tethering.

Kv7 channels can function without constitutive calmodulin tethering.

M-channels are voltage-gated potassium channels composed of Kv7.2-7.5 subunits that serve as important regulators of neuronal excitability. Calmodulin binding is required for Kv7 channel function and mutations in Kv7.2 that disrupt calmodulin binding cause Benign Familial Neonatal Convulsions (BFNC)...

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Bibliographic Details
Main Authors: Juan Camilo Gómez-Posada, Paloma Aivar, Araitz Alberdi, Alessandro Alaimo, Ainhoa Etxeberría, Juncal Fernández-Orth, Teresa Zamalloa, Meritxell Roura-Ferrer, Patricia Villace, Pilar Areso, Oscar Casis, Alvaro Villarroel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21980481/?tool=EBI

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