The colonic epithelium plays an active role in promoting colitis by shaping the tissue cytokine profile.
Inflammatory bowel disease (IBD) is a chronic condition driven by loss of homeostasis between the mucosal immune system, the commensal gut microbiota, and the intestinal epithelium. Our goal is to understand how these components of the intestinal ecosystem cooperate to control homeostasis. By combin...
Main Authors: | Jesse Lyons, Phaedra C Ghazi, Alina Starchenko, Alessio Tovaglieri, Katherine R Baldwin, Emily J Poulin, Jessica J Gierut, Casie Genetti, Vijay Yajnik, David T Breault, Douglas A Lauffenburger, Kevin M Haigis |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2018-03-01
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Series: | PLoS Biology |
Online Access: | http://europepmc.org/articles/PMC5892915?pdf=render |
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