Immunohistochemical Detection and Localization of Somatostatin Receptor Subtypes in Prostate Tissue from Patients with Bladder Outlet Obstruction

Background and Aim of the Study: Scant information on the cellular distribution of the five somatostatin receptor (SSTR) subtypes in the normal prostate and in neoplasms of the prostate has been reported in very few studies in which techniques, such as in situ hybridization histochemistry, autoradio...

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Main Authors: Rodolfo Montironi, Liang Cheng, Roberta Mazzucchelli, Doriana Morichetti, Daniela Stramazzotti, Alfredo Santinelli, Gianluca Moroncini, Andrea B. Galosi, Giovanni Muzzonigro, Giancarlo Comeri, Jon Lovisolo, Sergio Cosciani-Cunico, Aldo V. Bono
Format: Article
Language:English
Published: Hindawi Limited 2008-01-01
Series:Cellular Oncology
Online Access:http://dx.doi.org/10.3233/CLO-2008-0433
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spelling doaj-47d2fe2f868e4e4f824be7bb869ec5732020-11-25T00:37:37ZengHindawi LimitedCellular Oncology1570-58701875-86062008-01-0130647348210.3233/CLO-2008-0433Immunohistochemical Detection and Localization of Somatostatin Receptor Subtypes in Prostate Tissue from Patients with Bladder Outlet ObstructionRodolfo Montironi0Liang Cheng1Roberta Mazzucchelli2Doriana Morichetti3Daniela Stramazzotti4Alfredo Santinelli5Gianluca Moroncini6Andrea B. Galosi7Giovanni Muzzonigro8Giancarlo Comeri9Jon Lovisolo10Sergio Cosciani-Cunico11Aldo V. Bono12Section of Pathological Anatomy, Polytechnic University of the Marche Region, School of Medicine, United Hospitals, Ancona, ItalyDepartment of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN, USASection of Pathological Anatomy, Polytechnic University of the Marche Region, School of Medicine, United Hospitals, Ancona, ItalySection of Pathological Anatomy, Polytechnic University of the Marche Region, School of Medicine, United Hospitals, Ancona, ItalySection of Pathological Anatomy, Polytechnic University of the Marche Region, School of Medicine, United Hospitals, Ancona, ItalySection of Pathological Anatomy, Polytechnic University of the Marche Region, School of Medicine, United Hospitals, Ancona, ItalySection of Internal Medicine, Department of Medical and Surgical Sciences, Polytechnic University of the Marche Region, School of Medicine, United Hospitals, Ancona, ItalyUrology Institute, Polytechnic University of the Marche Region, School of Medicine, United Hospitals, Ancona, ItalyUrology Institute, Polytechnic University of the Marche Region, School of Medicine, United Hospitals, Ancona, ItalyDepartment of Urology, Multimedica, Castellanza, ItalyDepartment of Urology, Ospedale Galmarini, Tradate, ItalyDepartment of Urology, University of Brescia, Brescia, ItalyDepartment of Urology, University of Brescia, Brescia, ItalyBackground and Aim of the Study: Scant information on the cellular distribution of the five somatostatin receptor (SSTR) subtypes in the normal prostate and in neoplasms of the prostate has been reported in very few studies in which techniques, such as in situ hybridization histochemistry, autoradiography, and more recently immunohistochemistry, have been applied. The aim of the study was to examine immunohistochemically the distribution and localization of these 5 subtypes in the various tissue components in normal prostate.http://dx.doi.org/10.3233/CLO-2008-0433
collection DOAJ
language English
format Article
sources DOAJ
author Rodolfo Montironi
Liang Cheng
Roberta Mazzucchelli
Doriana Morichetti
Daniela Stramazzotti
Alfredo Santinelli
Gianluca Moroncini
Andrea B. Galosi
Giovanni Muzzonigro
Giancarlo Comeri
Jon Lovisolo
Sergio Cosciani-Cunico
Aldo V. Bono
spellingShingle Rodolfo Montironi
Liang Cheng
Roberta Mazzucchelli
Doriana Morichetti
Daniela Stramazzotti
Alfredo Santinelli
Gianluca Moroncini
Andrea B. Galosi
Giovanni Muzzonigro
Giancarlo Comeri
Jon Lovisolo
Sergio Cosciani-Cunico
Aldo V. Bono
Immunohistochemical Detection and Localization of Somatostatin Receptor Subtypes in Prostate Tissue from Patients with Bladder Outlet Obstruction
Cellular Oncology
author_facet Rodolfo Montironi
Liang Cheng
Roberta Mazzucchelli
Doriana Morichetti
Daniela Stramazzotti
Alfredo Santinelli
Gianluca Moroncini
Andrea B. Galosi
Giovanni Muzzonigro
Giancarlo Comeri
Jon Lovisolo
Sergio Cosciani-Cunico
Aldo V. Bono
author_sort Rodolfo Montironi
title Immunohistochemical Detection and Localization of Somatostatin Receptor Subtypes in Prostate Tissue from Patients with Bladder Outlet Obstruction
title_short Immunohistochemical Detection and Localization of Somatostatin Receptor Subtypes in Prostate Tissue from Patients with Bladder Outlet Obstruction
title_full Immunohistochemical Detection and Localization of Somatostatin Receptor Subtypes in Prostate Tissue from Patients with Bladder Outlet Obstruction
title_fullStr Immunohistochemical Detection and Localization of Somatostatin Receptor Subtypes in Prostate Tissue from Patients with Bladder Outlet Obstruction
title_full_unstemmed Immunohistochemical Detection and Localization of Somatostatin Receptor Subtypes in Prostate Tissue from Patients with Bladder Outlet Obstruction
title_sort immunohistochemical detection and localization of somatostatin receptor subtypes in prostate tissue from patients with bladder outlet obstruction
publisher Hindawi Limited
series Cellular Oncology
issn 1570-5870
1875-8606
publishDate 2008-01-01
description Background and Aim of the Study: Scant information on the cellular distribution of the five somatostatin receptor (SSTR) subtypes in the normal prostate and in neoplasms of the prostate has been reported in very few studies in which techniques, such as in situ hybridization histochemistry, autoradiography, and more recently immunohistochemistry, have been applied. The aim of the study was to examine immunohistochemically the distribution and localization of these 5 subtypes in the various tissue components in normal prostate.
url http://dx.doi.org/10.3233/CLO-2008-0433
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